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Why is drug discovery important?

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  The goal of a preclinical drug discovery program is to deliver one or more clinical candidate molecules, each of which has sufficient evidence of biologic activity at a target relevant to a disease as well as sufficient safety and drug-like properties so that it can be entered into human testing. Most discovery programs seek to produce more than one candidate molecule because, as is shown in, many molecules do not move through the entire process because of problems with safety, kinetics, potency, intellectual property protection, or other factors. There is no simple formula for producing a viable clinical candidate molecule, although extensive collaboration of chemistry, biology, toxicology, and pharmacokinetics is almost universally the norm in modern drug discovery programs small molecule drug discovery programs typically produce massive amounts of data using high-throughput screening techniques that evaluate many compounds at many doses against many assays For more deatails :  Dru
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What is chemical name for drugs?

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  The chemical name is a scientific name based on the compound's chemical structure (e.g., 6-thioguanine) and is almost never used to identify the drug in a clinical or marketing situation. The generic name is granted by the USAN Council and is commonly used to identify a drug during its useful clinical lifetime. The company that patents the drug creates the brand name (trademark). This name identifies the drug during the 17 years that the company has exclusive rights to make, sell, and use it under patent law. The process for naming a marketable drug involves five steps: NCE submission and patent application, generic naming, brand naming, FDA review, and final approval. A marketed drug has three names: a chemical name, a generic name, and a brand name. A chemical name is given when a new chemical entity (NCE) is developed.   For more details: Drug Discovery Conference  
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What are organic drugs?

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  Organic drugs are natural substances extracted from plants and animals.   Examples of them include marijuana, heroin, opium, cocaine and hallucinogenic mushrooms . Currently, manufacturers of synthetic prescription drugs are held accountable when they produce their products, but even drug manufacturers find it in their best interest to alter drugs’ chemical compositions to make a cheaper product or to produce drugs faster. Many synthetic drugs can be used without causing serious harm. If a drug is taken as prescribed, the effects will be minimal, and generally outweighed by the benefits they provide for a medical condition. However all drugs cause a chemical reaction in the brain, so the longer someone uses any chemical, organic or synthetic, the more change it will cause For more details: Drug Discovery 2023
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What do you study in drug design?

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To undertake these courses, students are required to have knowledge about biology, biochemistry, chemistry, pharmacology, and general pathology, normally acquired from introductory courses for medicinal chemistry during a bachelor’s degree program ·          Multiple linear regression (MLR) (10) ·          Principal component analysis (PCA) (11) ·          Partial least-squares (PLS) (12,13) ·          Quantitative structure–activity relationships (QSAR) (14) ·          Three-dimensional QSAR (3D QSAR) (15) ·          Pharmacophore modeling (PM) (16) ·          Molecular docking (MDock) (17) To know more about Drug Discovery Join with us at Drug Discovery 2023, Which is going to be held at September 21-22, 2023 Paris, France For more details : Drug Discovery 2023
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What is the history of drug discovery?

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  Drug Discovery in modern times straddles three main periods. The first notable period can be traced to the nineteenth century where the basis of drug discovery relied on the serendipity of the medicinal chemists. The second period commenced around the early twentieth century when new drug structures were found, which contributed for a new era of antibiotics discovery The period also was revolutionized by the emergence of recombinant DNA technology, where it became possible to develop potential drugs target candidates. With all the expansion of new technologies and the onset of the "Omics" revolution in the twenty-first century, the third period has kick-started with an increase in biopharmaceutical drugs approved by FDA/EMEA for therapeutic use. To know more about Drug Discovery Join with us at drug discovery 2023 which is going to be held at September 21-22, 2023 Paris, France For more details : Drug Discovery 2023
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What was the first drug discovered?

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  The first synthetic drug, chloral hydrate, was discovered in 1869 and introduced as a sedative-hypnotic; it is still available today in some countries. The first pharmaceutical companies were spin-offs from the textiles and synthetic dye industry and owe much to the rich source of organic chemicals derived from the distillation of coal (coal-tar). The first analgesics and antipyretics, exemplified by phenacetin and acetanilide, were simple chemical derivatives of aniline and p-nitrophenol, both of which were byproducts from coal-tar. An extract from the bark of the white willow tree had been used for centuries to treat various fevers and inflammation. For more details : Drug discovery conference
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Early drug discovery and the rise of pharmaceutical chemistry?

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  Studies in the field of forensic pharmacology and toxicology would not be complete without some knowledge of the history of drug discovery, the various personalities involved, and the events leading to the development and introduction of new therapeutic agents. The first medicinal drugs came from natural sources and existed in the form of herbs, plants, roots, vines and fungi. Until the mid-nineteenth century nature's pharmaceuticals were all that were available to relieve man's pain and suffering.   The first synthetic drug, chloral hydrate, was discovered in 1869 and introduced as a sedative-hypnotic; it is still available today in some countries. The first pharmaceutical companies were spin-offs from the textiles and synthetic dye industry and owe much to the rich source of organic chemicals derived from the distillation of coal (coal-tar). The first analgesics and antipyretics, exemplified by phenacetin and acetanilide, were simple chemical derivatives of aniline and p
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